One thing I started a few years ago is weighing each case. You get much more consistent groups when the cases all weigh the same.
What is your goal in terms of group size at 100, though? If you're going for benchrest level consistency (sub-.2MOA) then yeah, it's probably worth it. In my case, I shoot PRS, so it's hard to justify the time and cost of weight/volume sorting brass when I am already getting groups in the .3-.4 range. It's rare for me to see a target where I am wishing my gun was printing in the .1-.2 range at a PRS event.