I just has a DOA. Attempted assault and robbery of a 65y/o F. She had some sort of short barreled revolver. First load was snake/bird shot the rest were FMJ.
She said she carried it this way to initially wound/deter anyone or thing, and if they kept coming she'd unload the rest. Her attacker, 6ft 200lb meathead on something. Snake shot took him in the face (R eye was a mess) but nothing penetrated deep. The rest were throat, nasal cavity, R eye and above the R eyebrow (traveled under the skin but over the skull and lodged at the base of his skull), fifth shot was a miss. No exit wounds so I am sure those little rounds bounced around. Guy was deader than shit and messed up. Initial shot was from about five feet. the rest were around ten to twelve.
Moral, anything is better than nothing and 22lr kills a lot of things/people. This dude didn't even have agonal respirations.